Abstract:This paper analyzed the present situation and characteristics of pine-wood nematode disease in Yichang city, and summarized the main practice and deficiency of the prevention and control of pine-wood nematode disease.Trough learning from the successful experiences and practices of pine-wood nematode disease in Jiangsu province and Huangshan city of Anhui province,we proposed the prevention and control strategy of pine-wood nematode disease in Yichang city, which are government domination,policy support,forest division policy,grasping the key,grasping the rules,and science and technology supporting.