Abstract:A new facial mask product containing natural antioxidant ingredients was developed. Using moisture rate, hydroxyl free radical clearance and tyrosinase activity inhibition rate of comprehensive evaluation of CE value as examining index, we optimized traditional mask formula, based on the contents of filmformer, moisturizing factor, film former and moisturizing factor ratio with three factors and five levels star test design, and the results were analyzed by linear and quadratic polynomial nonlinear fitting, forecast analysis and verification experiments. Further sensory evaluation and animal stimulation experiments were conducted. The optimal formula of the mask consists of 4.6 percent film formation agent, 2.4 percent moisturizer, and the ratio of film formation agent and moisturizer is 1.2. The difference between the predicted value and theoretical value of the moisture rate, hydroxyl radical scavenging rate and the activity inhibition rate of tyrosinase is 0.63 percent, 0.58 percent and 0.35 percent, respectively. The application effect of the mask shows that the mask contains no stimulating, sensitive ingredients, and the functional conditions are mild. The physicochemical and sensory evaluation indexes of the mask conform to the national accepted standards. Meanwhile, the animal experiments show no abnormalities. The star point designeffect surface method can optimize the preparation process of Indocalamus longiauritus leaves flavone oligomeric chitosan mask, and the theoretical model predicts well. Indocalamus longiauritus leaves flavonoid oligomer chitosan mask has a certain whitening, moisturizing and antiaging effect.